Mathias Middelboe

Structure of NO16, a marine non-tailed vibriophage with a global distribution

This study characterizes the structure of the non-tailed vibriophage NO16, revealing its capsid organization and potential host interaction mechanisms.

Slow to Start, Free at Last: Dual Effects of Mucin on Escherichia coli Phage T4

This study shows that soluble mucin glycans delay Escherichia coli phage T4 infection initiation but enhance virion stability and persistence in the gut.

Predicting Phage Host Interactions Across Taxonomic Levels: A Systematic Review and Meta-Analysis for Microbial Ecology

This study evaluates machine learning tools for predicting phage-host interactions across taxonomic levels, finding significant variability in performance, especially at finer resolutions like Family and Species.

Infauna selectively enhance DNA virus diversity and activity in marine sediments

The paper investigates how infauna affect DNA and RNA virus communities in marine sediments, finding increased DNA virus abundance and activity under higher infauna conditions.

Synergistic effects of commensals and phage predation in combating pathogen infections: a shrimp model

The paper shows that combining specific microbes with phage treatment improves pathogen exclusion in shrimp, highlighting the synergy between phage predation and microbial competition.

Spatial heterogeneity influences phage-host co-existence dynamics and phage resistance development in Vibrio anguillarum

This study shows that spatial structure in bacterial populations affects phage-host coexistence and resistance development in Vibrio anguillarum.

Diversification of Pseudomonas aeruginosa biofilm populations under repeated phage exposures decreases the efficacy of the treatment

This study shows that repeated phage exposure to P. aeruginosa biofilms reduces phage efficacy due to genetic changes that confer resistance and tolerance.