Xinxin Du

This study introduces a biophysical model that couples adhesion complex dynamics to intracellular mechanics, revealing multicellular patterns like polarization and stress chains.

The paper investigates how Planar Cell Polarity (PCP) directs cell crawling during hair placode morphogenesis, showing that PCP drives anterior-directed crawling at the basal surface, generating counter-rotational cell motion at the apical surface.

The paper develops two models to explain how stem cell scaling occurs during organ resizing in Drosophila midgut by linking commitment rate to stem cell proportion.