Danelle Devenport

The paper shows PCP proteins transition between mobile and stable states during mitosis, losing and restoring planar cell polarity through lateral diffusion and adhesive interactions.

The paper investigates how Planar Cell Polarity (PCP) directs cell crawling during hair placode morphogenesis, showing that PCP drives anterior-directed crawling at the basal surface, generating counter-rotational cell motion at the apical surface.

A novel Cfap298 mutation disrupts left-right patterning in mice by impairing ciliary motility, revealing a conserved protein region essential for this function across species.

This study shows melanoblasts use atypical E-cadherin attachments to migrate through epithelial layers without disrupting the barrier.

This paper introduces KimmelNet, a deep learning model that predicts zebrafish embryo age from 2D brightfield images and detects developmental delay between populations.

The paper studies epidermal planar polarity reversal in the fancy rosette mouse, finding a region-specific rotation of the PCP axis due to a mutation in Fzd6.

The paper shows that phosphorylation of a specific tyrosine in Vang/Vangl regulates its interaction with Pk and Dsh/Dvl, promoting the formation of the Vang/Vangl-Pk complex during PCP establishment.

This study identifies a novel role for mesenchymal Vangl in airway elongation and widening during lung development, independent of the planar cell polarity complex.

The paper shows Vangl in the pulmonary mesenchyme, not the airway epithelium, is critical for mesenchymal thinning and sacculation during lung development, independent of Celsr1.