Author

Harini Ramalingam

The University of Texas Southwestern Medical CenterORCID 0000-0001-7029-9069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jesus Alvarez· 2 shared Laurence Michael BiggersiD· 2 shared Patricia Cobo-StarkiD· 2 shared Ronak LakhiaiD· 2 shared Vishal PateliD· 2 shared Andrea FlateniD· 1 shared Arvind SomasundarumiD· 1 shared Chun-Mien Chang· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

Jesus Alvarez

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2 papers

Recent·Most cited

GeneticsNucleic Acids ResearchPeer-reviewedJan 6, 2026

Disruption of a six-nucleotide miRNA motif improves PKD1 dosage and ameliorates polycystic kidney disease

Ronak Lakhia, Chunzi Song, Laurence Michael Biggers…·Vishal Patel

This paper identifies a six-nucleotide miRNA motif that represses PKD1 and shows that disrupting it improves PKD1 dosage and reduces cyst growth in ADPKD models.

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mousebulk RNA-seq

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GeneticsNature CommunicationsPeer-reviewedAug 14, 2022

PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression

Ronak Lakhia, Harini Ramalingam, Chun-Mien Chang…·Vishal Patel

This study identifies cis-inhibition of PKD1 and PKD2 mRNAs via miR-17 in ADPKD and shows that disrupting this mechanism reduces cyst growth in multiple models.

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mousehuman

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