Magdalena Maria Brislinger-Engelhardt

This study identifies novel functions of Foxi1 in regulating mucociliary progenitor cells and ionocyte specification through transcriptional and epigenetic mechanisms in Xenopus laevis.

The paper identifies a homozygous WNT11 variant causing laterality, heart, and renal defects in an infant and shows its loss-of-function in Xenopus embryos.

The paper investigates how Notch signaling and Hes factors regulate mucociliary cell fate specification in Xenopus tadpole epidermis through competitive de-repression.

The paper shows that multiciliated cells can trans-differentiate into secretory cells during developmental remodeling in Xenopus, induced by changes in signaling pathways.

This study identifies ΔN-Tp63 as a key mediator of Wnt/β-catenin signaling in basal stem cells of mucociliary epithelia, showing its role in inhibiting differentiation and promoting hyperplasia.