Author

Alexia Tasca

University of FreiburgORCID 0000-0003-4269-0313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Magdalena Maria Brislinger-EngelhardtiD· 3 shared Maximilian Haas· 3 shared Peter WalentekiD· 3 shared Africa Temporal-PloiD· 1 shared Aisha Andricek· 1 shared Clemens KreutziD· 1 shared Damian WeberiD· 1 shared Dingyuan Iris SuniD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Magdalena Maria Brislinger-EngelhardtORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintFeb 15, 2023

Temporal Notch signaling and Hes-mediated competitive de-repression regulate mucociliary cell fates in Xenopus

Magdalena Maria Brislinger-Engelhardt, Mona Hansen, Tim Litwin…·Peter Walentek

The paper investigates how Notch signaling and Hes factors regulate mucociliary cell fate specification in Xenopus tadpole epidermis through competitive de-repression.

6 citations

non-human primatestatistical model

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Developmental BiologybioRxivPreprintApr 16, 2020

A changing signaling environment induces multiciliated cell trans-differentiation during developmental remodeling

Alexia Tasca, Martin Helmstädter, Magdalena Maria Brislinger-Engelhardt…·Peter Walentek

The paper shows that multiciliated cells can trans-differentiate into secretory cells during developmental remodeling in Xenopus, induced by changes in signaling pathways.

2 citations

mouseexperimental assay

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Developmental BiologyCell ReportsPeer-reviewedSep 1, 2019

ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia

Maximilian Haas, José Luis Gómez-Vázquez, Dingyuan Iris Sun…·Peter Walentek

This study identifies ΔN-Tp63 as a key mediator of Wnt/β-catenin signaling in basal stem cells of mucociliary epithelia, showing its role in inhibiting differentiation and promoting hyperplasia.

63 citations

mousehuman

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