Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewed
PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity
Irma G. Domínguez-Vigil, Kishore Banik, Marta Baro…·Thomas J. Hayman
This study shows that PLK4 inhibition with CFI-400945 enhances radiosensitivity of NSCLC cells but not normal fibroblasts by increasing mitotic catastrophe and centrosome amplification.
6 citations