Author

Irma G. Domínguez-Vigil

Yale UniversityORCID 0000-0003-4687-6318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Joseph N. ContessaiD· 1 shared Kishore BanikiD· 1 shared Marta BaroiD· 1 shared Thomas J. HaymaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Joseph N. ContessaORCID

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1 paper

Recent·Most cited

Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewedApr 29, 2025

PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity

Irma G. Domínguez-Vigil, Kishore Banik, Marta Baro…·Thomas J. Hayman

This study shows that PLK4 inhibition with CFI-400945 enhances radiosensitivity of NSCLC cells but not normal fibroblasts by increasing mitotic catastrophe and centrosome amplification.

6 citations

humanexperimental assay

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