Molecular BiologybioRxivPreprint
Senescence in yeast is associated with chromosome XII fragments rather than ribosomal DNA circle accumulation
Andre Zylstra, Hanane Hadj‐Moussa, Dorottya Horkai…·Jonathan M. Houseley
This study shows that chromosome XII fragments, not ERCs, drive senescence in yeast, despite rDNA copy number increases with age.
DOI 10.1101/2022.07.14.500009