Sara Mirsadeghi

This study shows APOE4 affects cortical neurodevelopment and network formation in human brain organoids by altering cell types, increasing cell death, and disrupting GABA signaling.

This study investigates the effects of ARX poly-alanine mutations in human brain organoids, revealing altered interneuron migration and cortical neuron development.

This study transplants autologous neural stem cells into Rhesus monkeys with spinal cord injury, showing functional and structural recovery without adverse effects.

This study develops a CNN-RNN deep learning method to automatically detect irregular rhythms and abnormal waveforms in field potentials from human iPSC-derived cardiomyocytes.