Alison L. Barth

This study shows that training in a whisker-based task reduces PV-mediated inhibition in female mice's L2/3 pyramidal neurons, suggesting sex-specific plasticity in cortical circuits during learning.

The paper identifies subtype-specific plasticity in SST neurons during sensory learning and develops a classifier to predict learning-associated response plasticity.

The paper shows that learning alters neocortical somatostatin inhibition in a stimulus-reward dependent manner, specifically reducing inhibition in superficial layers of mouse somatosensory cortex.

This paper describes an automated homecage system for training mice in multiwhisker discrimination learning using air current stimulation and water reward, showing rapid learning and performance improvements.

The paper shows that during sensory learning in mice, PV inhibition in L2/3 pyramidal neurons decreases, enabling increased recurrent activity, but not in L5 neurons.

The paper develops genetically-encoded reagents for cell-type specific synapse labeling and connectivity analysis in mouse brain tissue, revealing PV inputs as the dominant inhibitory source onto L2 pyramidal neurons.