Eunsol Park

This study shows that training in a whisker-based task reduces PV-mediated inhibition in female mice's L2/3 pyramidal neurons, suggesting sex-specific plasticity in cortical circuits during learning.

The paper identifies subtype-specific plasticity in SST neurons during sensory learning and develops a classifier to predict learning-associated response plasticity.

The paper shows that learning alters neocortical somatostatin inhibition in a stimulus-reward dependent manner, specifically reducing inhibition in superficial layers of mouse somatosensory cortex.

The paper shows that during sensory learning in mice, PV inhibition in L2/3 pyramidal neurons decreases, enabling increased recurrent activity, but not in L5 neurons.

This study shows that locomotion does not enhance spatial acuity perception in mice, despite increasing responsiveness to visual stimuli.

The paper develops genetically-encoded reagents for cell-type specific synapse labeling and connectivity analysis in mouse brain tissue, revealing PV inputs as the dominant inhibitory source onto L2 pyramidal neurons.