Author

Apurva A. Govande

Harvard UniversityORCID 0000-0001-7112-9811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

Aaron T. WhiteleyiD· 1 shared Albur Hassan· 1 shared Brooke RamseyiD· 1 shared Catherine Trautman· 1 shared Clayton M. CareyiD· 1 shared Gerald R. SmithiD· 1 shared Hoong Chuin LimiD· 1 shared Irem ÜnlüiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Aaron T. WhiteleyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 1, 2026

RecBCD Prevents Bacterial Autoimmunity by Clearing Self-DNA Ends Produced During Replication Termination

Apurva A. Govande, Brooke Ramsey, Irem Ünlü…·Hoong Chuin Lim

The paper shows that RecBCD clears self-DNA ends during bacterial replication termination to prevent autoimmunity, similar to TREX1 and DBR1 in eukaryotes.

DOI 10.64898/2026.09.30.755081

bacteria (other)experimental assay

𝕏 PostBluesky

GeneticsCell Host & MicrobePeer-reviewedJan 31, 2019

Recurrent loss-of-function mutations reveal costs to OAS1 antiviral activity in primates

Clayton M. Carey, Apurva A. Govande, Juliane M. Cooper…·Nels C. Elde

The paper identifies recurrent loss-of-function mutations in OAS1 across primates, showing that the cytotoxic effects of OAS1 activation can outweigh its antiviral benefits, leading to reduced catalytic activity.

44 citations

non-human primateexperimental assay

𝕏 PostBluesky