An early mTOR-dependent window during human T cell activation programs T cell state
Maria Valeria Lattanzio, Anouk P. Jurgens, Arie Johan Hoogendijk…·Monika C. Wolkers
This study identifies an early mTOR-dependent window during human T cell activation that programs cytotoxic fate or memory-like state, with transient inhibition promoting memory while preserving effector functions.