Branka Popović

The paper identifies RNA binding proteins and cis-regulatory elements that control translation in human effector T cells through multi-omics and machine learning analysis.

This study identifies a novel mTOR-dependent mechanism regulating cytokine production in T cells through 3UTR AU-rich elements and DDX21 binding.

This study uses single-molecule FISH to analyze cytokine mRNA dynamics in T cells, revealing transcriptional heterogeneity and post-transcriptional regulation by HuR.

The paper maps the ZFP36L1 interactome in human T cells using proximity labeling, revealing its role in post-transcriptional regulation and protein expression.

This study shows that deleting both ZFP36L1 and ZFP36L2 in T cells greatly increases cytokine production but reduces cell viability and signaling.

This study shows ZFP36L2 regulates IFNγ production in T cells differently depending on activation context and time, by destabilizing Ifng mRNA in an AU-rich element-dependent manner.