Michael Tsang

This study identifies cited4a as a regulator that suppresses cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration.

The paper investigates the role of sap130a in zebrafish heart development, showing it regulates SHF cell accretion and maturation, leading to ventricular hypoplasia.

The paper identifies metabolic regulation in left-right patterning using spatial transcriptome data, linking glycolysis and Bmp7 to heart and gut looping.

This paper demonstrates the use of PhoCl, a photocleavable fluorescent protein, to achieve optical control over protein cleavage in zebrafish embryos, enabling light-triggered protein translocation and apoptosis.

This study identifies foxm1 as essential for cardiomyocyte proliferation in adult zebrafish after injury, revealing its role in regulating cell cycle genes and enabling regeneration.

This paper introduces a method to control CRISPR/Cas9 activity using light-activated guide RNAs, enabling precise spatiotemporal gene editing in cells and zebrafish embryos.

The paper shows myosin 1d is essential for establishing left-right asymmetry in zebrafish through actin-myosin driven chirality.