Author

Xavier Lahaye

Université Paris Sciences et LettresORCID 0000-0001-7124-1707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Nicolas ManeliD· 2 shared Brianna Rodgers· 1 shared Clotilde ThéryiD· 1 shared David BernardiD· 1 shared David VindrieuxiD· 1 shared Delphine Goehrig· 1 shared Ester Piovesana· 1 shared Federico Cocozza· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Nicolas ManelORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJul 1, 2025

DNA methylation protects cancer cells against senescence

Xiaoying Chen, Kosuke Yamaguchi, Brianna Rodgers…·Pierre‐Antoine Defossez

The paper shows that reduced DNA methylation in cancer cells leads to senescence without DNA damage, involving p21 and cGAS, and demonstrates this in vivo.

17 citationstop 1%

humanDNA methylation

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MicrobiologyJournal of Extracellular VesiclesPeer-reviewedDec 28, 2020

Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus

Federico Cocozza, Ester Piovesana, Nathalie Névo…·Lorena Martin-Jaular

The paper shows that extracellular vesicles with ACE2 can block SARS-CoV-2 infection more effectively than soluble ACE2.

DOI 10.1002/jev2.12050

experimental assayhost-pathogen & immune response

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