Author
University of ChicagoORCID 0000-0001-7147-0614Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Chaitra Rao, Fei Huang, Saptarshi Roy…·Emily Kristen Sims
The paper identifies an IFN-induced PD-L1 splice variant, PD-L1Δ3, which is retained intracellularly and fails to suppress T cell activation, altering β cell immune communication in type 1 diabetes.
Kerim B. Kaylan, Xia S. Saavedra, Christian Checkcinco…·Sarah A. Tersey
This study identifies GPR31 as a key inflammatory regulator in pancreatic islets, showing its role in β-cell stress and macrophage activation in type 1 diabetes.
Kerim B. Kaylan, Titli Nargis, Kayla T. Figatner…·Sarah A. Tersey
This study shows that inhibiting 12-LOX improves glucose homeostasis and reduces obesity-related inflammation in human gene replacement mice.
Titli Nargis, Charanya Muralidharan, Jacob R. Enriquez…·Raghavendra G. Mirmira
This study shows that inhibiting 12-LOX with VLX-1005 delays autoimmune diabetes onset in human gene replacement mice by altering inflammatory pathways and immune cell infiltration.