Sixiong Lin

This study shows that vinculin inhibits Mef2c-driven sclerostin expression in osteocytes, promoting bone formation in mice by enhancing estrogen regulation.

This study explores the feasibility of using selective germline genome-edited pig meninges grafts for abdominal wall closure in damage control surgery, showing successful integration and revascularization in a rabbit model.

The paper creates a genetically modified pig with specific gene edits to enable immune tolerance in non-human primates and demonstrates long-term graft survival without immunosuppression.