Guozhi Xiao

This study uses an inducible X-CreERT2/Ai9 system to map Fermt2 (Kindlin-2) expression across all mouse tissues, identifying both known and novel expression patterns and establishing a platform for organism-wide gene expression profiling.

The paper identifies Sialin2 as a mammalian nitrate sensor that sustains mitochondrial homeostasis by activating AMPK and enhancing mitochondrial function.

This study identifies multiple cullin-associated E3 ligases that regulate cyclin D1 protein stability through ubiquitination and proteasome degradation, affecting cell cycle progression and proliferation.

This study shows that Axin1 deletion in mice causes fibular hemimelia by disrupting β-catenin and BMP signaling during limb development.

This study shows that vinculin inhibits Mef2c-driven sclerostin expression in osteocytes, promoting bone formation in mice by enhancing estrogen regulation.