Linxian X. Li

Selective Germline Genome Edited Pig Meninges Grafts for the Abdominal Wall Closure in Damage Control Surgery

This study explores the feasibility of using selective germline genome-edited pig meninges grafts for abdominal wall closure in damage control surgery, showing successful integration and revascularization in a rabbit model.

Selective germline genome edited pigs and their long immune tolerance in Non Human Primates

The paper creates a genetically modified pig with specific gene edits to enable immune tolerance in non-human primates and demonstrates long-term graft survival without immunosuppression.

CRISPR-Cas12b-assisted nucleic acid detection platform

The paper develops HOLMESv2, a one-step nucleic acid detection platform combining LAMP and Cas12b for convenient and efficient detection.