Cindy Fang

The paper perturbs schizophrenia risk genes in mice to identify ciliary transcriptional programs as a potential downstream mechanism of disease.

This study maps molecular and genetic signatures of schizophrenia in human prefrontal cortex across spatial scales, revealing altered BDNF-TrkB signaling and inhibitory circuit dysfunction.

spaTransfer transfers cell type or spatial domain labels between single-cell and spatial transcriptomics datasets using non-negative matrix factorization and a multinomial model.

The paper applies 288 scRNA-seq pipelines to 86 datasets and builds machine learning models to predict pipeline performance based on dataset and pipeline characteristics.