Author

Jiazhou Chen

Guangdong University of TechnologyORCID 0000-0001-7171-9547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:imputation· 1 Organism:mouse· 1

Frequent Co-Authors

Hongmin CaiiD· 2 shared Bin LaniD· 1 shared Chen‐Song ZhangiD· 1 shared Chong ZhangiD· 1 shared Dongxu CheniD· 1 shared Fangfang CheniD· 1 shared Fei QiiD· 1 shared Fuqing Chen· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Hongmin CaiORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 24, 2026

RADF: Reference-Anchored Dynamic Flow for Spatial Perturbation Profile Completion

Hongmin Cai, Wanghou, Jiazhou Chen…·Xiaoqi Sheng

RADF completes spatial perturbation profiles by combining reference-supported population anchors with location-dependent refinement, reducing macro E-distance by 70.6%.

DOI 10.64898/2026.08.20.745474

spatial transcriptomicsstatistical model

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BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewedDec 26, 2025

Unveiling Tissue Structure and Tumor Microenvironment from Spatial Omics by Hypergraph Learning

Yi Liao, Chong Zhang, Zhikang Wang…·Hongmin Cai

HyperSTAR identifies spatial domains across resolutions using hypergraph learning, outperforming existing methods in spatial omics analysis and revealing breast cancer spatial heterogeneity.

2 citations

humanspatial transcriptomics

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ImmunologyCell ResearchPeer-reviewedNov 25, 2025

AMPK acts to remove immune barriers to CD8+ T cell-mediated immunity against hepatocellular carcinoma

Hui-Hui Hu, Xuefeng Wang, Bin Lan…·Sheng‐Cai Lin

This study shows that aldometanib activates AMPK to enhance CD8+ T cell infiltration and control hepatocellular carcinoma growth in immune-competent mice.

16 citationstop 4%

mouseexperimental assay

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