Jörg M. Grandl

This study investigates how alternative splicing of Piezo2 affects its sensitivity to membrane tension using electrophysiology and microscopy.

This study shows that Piezo1 conformational changes, not ion permeation, modulate TREK1 K2P channels, suggesting conformational signaling as a potential mechanism.

This study quantifies the mechanical energy detection capabilities of cells using force-gated ion channels, revealing their sensitivity and response dynamics.