Author

Amanda H. Lewis

Duke Medical CenterORCID 0000-0001-7316-9729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:electronic health records· 1 Assay:electrophysiology· 1 Organism:human· 1

Frequent Co-Authors

Jörg M. GrandliD· 2 shared Marie E. CroniniD· 1 shared Michael J. SindoniiD· 1 shared Michael N. YoungiD· 1 shared Stefan ZauscheriD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

Jörg M. GrandlORCID

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2 papers

Recent·Most cited

BiophysicsNeuronPeer-reviewedJul 22, 2024

Piezo1 ion channels are capable of conformational signaling

Amanda H. Lewis, Marie E. Cronin, Jörg M. Grandl

This study shows that Piezo1 conformational changes, not ion permeation, modulate TREK1 K2P channels, suggesting conformational signaling as a potential mechanism.

34 citationstop 4%

electrophysiologyexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 17, 2022

The energetics of rapid cellular mechanotransduction

Michael N. Young, Michael J. Sindoni, Amanda H. Lewis…·Jörg M. Grandl

This study quantifies the mechanical energy detection capabilities of cells using force-gated ion channels, revealing their sensitivity and response dynamics.

2 citations

humanelectronic health records

𝕏 PostBluesky