Author

Karisa C. Schreck

Johns Hopkins UniversityORCID 0000-0001-7181-3269Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abiola Abdulrahman AyanlajaiD· 1 shared Calixto‐Hope G. LucasiD· 1 shared Christine A. PratilasiD· 1 shared Jean M. Mulcahy LevyiD· 1 shared Jiawan WangiD· 1 shared Kriti LalwaniiD· 1 shared Maria IoannouiD· 1 shared Michael ChangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abiola Abdulrahman AyanlajaORCID

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1 paper

Recent·Most cited

Cancer BiologyNeuro-Oncology AdvancesPeer-reviewedJan 1, 2025

Combined inhibition of SHP2 overcomes adaptive resistance to type 1 BRAF inhibitors in BRAF V600E-driven high-grade glioma

Abiola Abdulrahman Ayanlaja, Michael Chang, Kriti Lalwani…·Karisa C. Schreck

This study shows that combining SHP2 inhibition with BRAF inhibitors overcomes resistance in BRAF V600E-driven gliomas by suppressing RAS/ERK signaling and preventing tumor growth.

6 citations

humanbulk RNA-seq

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