Author

Jiawan Wang

Johns Hopkins UniversityORCID 0000-0002-2137-1826Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Calixto‐Hope G. LucasiD· 2 shared Christine A. PratilasiD· 2 shared Abiola Abdulrahman AyanlajaiD· 1 shared Adam Scott LeviniD· 1 shared Alexandra J. ScottiD· 1 shared Allan J. Belzberg· 1 shared Ana CalizoiD· 1 shared Angela C. HirbeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioinformatics

Calixto‐Hope G. LucasORCID

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2 papers

Recent·Most cited

Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset

Jineta Banerjee, Yang Lyu, Stavriani C. Makri, Alexandra J. Scott, Lindy Zhang, Ana Calizo, Kai Pollard, Kuangying Yang, John M. Gross, Calixto‐Hope G. Lucas, Jiawan Wang, Adam Scott Levin, Allan J. Belzberg, Carlos Guillermo Romo, Robert J. Allaway, , Christine A. Pratilas

The paper provides an integrated genomic analysis of NF1-associated peripheral nerve sheath tumors using RNAseq and WES data from 73 and 114 samples, respectively, accessible via the NF Data Portal.

Scientific Data · Jul 15, 2025Peer-reviewedBioinformatics

Combined inhibition of SHP2 overcomes adaptive resistance to type 1 BRAF inhibitors in BRAF V600E-driven high-grade glioma

Abiola Abdulrahman Ayanlaja, Michael Chang, Kriti Lalwani, Maria Ioannou, Jiawan Wang, Shreya Jagtap, Yanbo Yang, Calixto‐Hope G. Lucas, Jean M. Mulcahy Levy, Robyn D. Gartrell, Christine A. Pratilas, Karisa C. Schreck

This study shows that combining SHP2 inhibition with BRAF inhibitors overcomes resistance in BRAF V600E-driven gliomas by suppressing RAS/ERK signaling and preventing tumor growth.

Neuro-Oncology Advances · Jan 1, 2025Peer-reviewedCancer Biology