Lianna Y. D’Brant

This study shows that neuronal glutamate transporter EAAC1 modulates synaptic excitation and lateral inhibition in D1-MSNs, affecting behavior through gain modulation and reduced firing sensitivity.

The paper shows circadian rhythms in hippocampal CA1 neurons and astrocytes affect synaptic plasticity through changes in NMDA receptor expression and astrocytic proximity to synapses, altering glutamate clearance and cognitive processing.

The paper investigates how EAAC1 affects dopaminergic signaling and compulsive behaviors in mice by modulating mGluRI activation and D1R expression in the striatum.