Author
Boston Children's HospitalORCID 0000-0001-7851-8617Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Nadezhda V. Terekhanova, Xiaolong Chen, Kin-Hoe Chow…·Jinghui Zhang
The paper identifies non-coding somatic variants in TAL1 regulatory regions that reactivate enhancers normally active in hematopoietic stem cells in T-lineage acute lymphoblastic leukemia.
Limeng Pu, Karol A. Szlachta, Virginia A. Valentine…·Jinghui Zhang
Seq2Karyotype (S2K) enables in-silico karyotyping from whole-genome sequencing data, revealing intratumoral heterogeneity and evolutionary trajectories in cancer samples.
Nina Weichert‐Leahey, Alla Berezovskaya, Mark W. Zimmerman…·Alfred Thomas Look
This study shows that inhibiting KAT6A/B with PF-9363 enhances retinoid efficacy and improves GD2-targeted immunotherapy in neuroblastoma.
Víctor Llombart, David O’Connor, Jonas Demeulemeester…·Marc R. Mansour
This study identifies acidic patches in the MYC N-terminal disordered domain essential for oncogenesis and chromatin interaction, offering new therapeutic targets.
Boyang Zhang, Alexander J. Murison, Angelica Varesi…·Stanley W.K. Ng
This study identifies distinct gene regulatory networks in hematopoietic stem cells and leukemia stem cells using integrated gene expression and chromatin accessibility data from AML patients and human umbilical cord blood.