Vijayalakshmi Kandasamy

The paper uses automated mini-bioreactors to study the temporal dynamics and multi-omics responses of CRISPRi knockdowns in Pseudomonas putida, identifying a critical time window for phenotypic impact.

The paper engineers Pseudomonas putida to strictly metabolize methanol through seven mutations, enabling growth on methanol as the sole carbon source.

The paper develops a yeast mating platform to screen fungal GPCR-ligand interactions and identifies peptides that modulate fungal communication.

This study combines ALE and WT variants to explore sequence solutions for industrial tolerance in E. coli, finding that WT variants can provide greater benefits and help identify feasible genome design variables.