Carsten Patrick Ade

The paper identifies a link between replication-coupled chromatin assembly and ATR/CHK1 signaling in suppressing DNA damage and MMB-dependent mitotic transcription.

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

The paper shows that TFIIIC binds MYCN and limits non-phosphorylated RNA Polymerase II accumulation at promoters, but does not affect MYCN-dependent gene expression or transcription elongation.

This study identifies NEAT1 as a regulator of genome stability through m6A methylation-dependent control of CHD4 in response to DNA damage.

The paper shows that NONO relocalizes to the nucleolus via diNARs to shield DNA breaks from aberrant transcripts, promoting repair.

This study shows that oncogenic YAP alters chromatin accessibility and activity, driving cell cycle gene expression and migration through enhancer-mediated mechanisms.

The paper shows that YAP interacts with the MMB complex to regulate cardiomyocyte proliferation through shared control of cell cycle genes.