Author

Steffi Herold

University of Würzburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Carsten Patrick AdeiD· 3 shared Gabriele BücheliD· 3 shared Martin EilersiD· 3 shared Christina Schülein‐Völk· 2 shared Peter GallantiD· 2 shared Raphael Silveira VidaliD· 2 shared Ana Cetkovic· 1 shared Angela RiedeliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Carsten Patrick AdeORCID

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Author profile →

3 papers

Recent·Most cited

MYC/MIZ1 suppression of lysosomal protein degradation drives immune evasion in pancreatic ductal adenocarcinoma

Bastian Krenz, Toshitha Kannan, Greta Mattavelli, Werner Schmitz, Anneli Gebhardt-Wolf, Mara John, Ana Cetkovic, Arpa Aintablian, Stella Caviccioli, Lukas Nowak, Sarah Bopp, Christina Schuelein‐Voelk, Carsten Patrick Ade, Steffi Herold, Julian Bender, , Martin Eilers

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

bioRxiv · Jul 23, 2026 · PreprintCancer Biology

A trimeric USP11/USP7/TCEAL1 complex stabilizes RNAPII during early transcription to sustain oncogenic gene expression

Markus Dehmer, Peter Gallant, Steffi Herold, Giacomo Cossa, Francesca Conte, Jan Köster, Florian Sauer, Christina Schülein‐Völk, Carsten Patrick Ade, Raphael Silveira Vidal, Caroline Kisker, Rogier Versteeg, Petra Beli, Seychelle M. Vos, Martin Eilers, Gabriele Büchel

bioRxiv · Jul 29, 2024 · PreprintCancer Biology

Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II

Raphael Silveira Vidal, Eoin N. Leen, Steffi Herold, Mareike Müller, Daniel Fleischhauer, Christina Schülein‐Völk, Dimitrios Papadopoulos, Isabelle Röschert, Leonie Uhl, Carsten Patrick Ade, Peter Gallant, Richard W. Bayliss, Martin Eilers, Gabriele Büchel

The paper shows that TFIIIC binds MYCN and limits non-phosphorylated RNA Polymerase II accumulation at promoters, but does not affect MYCN-dependent gene expression or transcription elongation.

eLife · Feb 7, 2024Peer-reviewedMolecular Biology