Author

Bastian Krenz

University of WürzburgORCID 0000-0003-1889-3022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Martin EilersiD· 2 shared Toshitha KannaniD· 2 shared Amel Aziba· 1 shared Ana Cetkovic· 1 shared Angela RiedeliD· 1 shared Anneli Gebhardt-Wolf· 1 shared Arpa AintablianiD· 1 shared Bettina WarscheidiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Martin EilersORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 23, 2026

MYC/MIZ1 suppression of lysosomal protein degradation drives immune evasion in pancreatic ductal adenocarcinoma

Bastian Krenz, Toshitha Kannan, Greta Mattavelli…·Martin Eilers

This study shows that MYC suppresses lysosomal protein degradation in pancreatic ductal adenocarcinoma, promoting immune evasion by altering amino acid availability and immune cell responses.

DOI 10.64898/2026.07.23.740267

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintDec 6, 2024

RNA-mediated MYC multimerization suppresses innate immune signaling

Leonie Uhl, Amel Aziba, Sinah Löbbert…·Martin Eilers

This study shows that MYC multimerization driven by RNA binding suppresses innate immune signaling by promoting exosome recruitment to R-loops and preventing immunogenic RNA accumulation.

1 citation

humanmultiome

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