Author

Jiaxin Huang

Northeast Agricultural UniversityORCID 0000-0001-7232-9313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Binbin CheniD· 1 shared Bo Jiang· 1 shared Guangwei MaiD· 1 shared Hongxun Gao· 1 shared Hui zi LiiD· 1 shared Jing DingiD· 1 shared Jingzhen Liang· 1 shared Luyao HuangiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioengineering

Binbin ChenORCID

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3 papers

Recent·Most cited

Intranuclear polyglycine aggregation drives neurodegeneration through epigenetic repression of chromatin accessibility and transcription

Yangye Lian, Shaoping Zhong, Jiaxin Huang, Luyao Huang, Yuzhe Li, Jingzhen Liang, Xin Wang, Jing Ding

This study shows intranuclear polyG aggregates cause more severe neurodegeneration than cytoplasmic ones by repressing chromatin accessibility and transcription through epigenetic mechanisms.

bioRxiv · May 14, 2026 · PreprintNeuroscience

Multicopper oxidase mediated single-carbon insertion for skeletal remodeling

Bo Jiang, Binbin Chen, Hongxun Gao, Jiaxin Huang, Xiao Liu, Mingjie Ma, Yajie Alison Wang

This paper introduces a multicopper oxidase-catalyzed method for single-carbon insertion in skeletal editing, enabling the synthesis of bioactive compounds with improved antibacterial activity.

bioRxiv · Mar 31, 2026 · PreprintBioengineering

An upstream open reading frame represses translation of chicken PPARγ transcript variant 1

Yankai Chu, Jiaxin Huang, Guangwei Ma, Tingting Cui, Xiaohong Yan, Hui zi Li, Ning Wang

This study identifies an upstream open reading frame (uORF) in the 5' UTR of chicken PPARγ1 that represses its translation.

Frontiers in Genetics · Feb 28, 2020Peer-reviewedMolecular Biology