Anne‐Sophie Archambault

The paper shows beta cells transfer mitochondria to islet macrophages, enhancing their protein synthesis and altering gene expression, suggesting a new communication mechanism in islet homeostasis.

This paper develops and validates versatile electroporation protocols for efficient CRISPR-RNP delivery in multiple primary mouse hematopoietic cells, achieving high gene knockout efficiency with minimal cell damage.

This study shows CD8+ T cells adapt to nutrient stress by reconfiguring gene-regulatory and metabolic networks, enabling functional resilience and anti-tumor immunity.

This paper introduces CloneSelect, a multi-kingdom genetic barcoding system that enables precise isolation of target clones using CRISPR base editing to trigger reporter gene expression.