Montana Knight

This study identifies altered purinergic signaling and CD8+ T cell dysregulation in STAT3 GOF syndrome, showing partial normalization with JAK inhibitors.

This study identifies T cell dysregulation in pediatric obesity and shows that these changes persist despite weight loss.

This study shows that environmental branched-chain amino acids regulate ASC translation and NLRP3 inflammasome assembly through mTOR-dependent translational bursting.

This study shows Enterococcus faecalis influences phase variation in Clostridioides difficile, altering its phenotypes through the CmrRST system.

This study shows CD8+ T cells adapt to nutrient stress by reconfiguring gene-regulatory and metabolic networks, enabling functional resilience and anti-tumor immunity.

This study uses RNA-Seq data from GeneLab to assess DNA sequence variants linked to spaceflight stress, finding more mutations in spaceflight samples than controls.