This study uses mendelian randomization to identify proteins downstream of Lp(a) and finds they are associated with inflammation and coagulation pathways related to cardiovascular disease.

medRxiv · Apr 22, 2026 · PreprintGenetic & Genomic Medicine

Angiocrine FSTL1 insufficiency leads to atrial and vein wall fibrosis via SMAD3 activation

Haijuan Jiang, Luqing Zhang, Xuelian Liu, Wei Sun, Katsuhiro Kato, Chuankai Chen, Xiao Li, Taotao Li, Zhiliang Sun, Wencan Han, Fujing Zhang, Qi Xiao, Zhongzhou Yang, Junhao Hu, Zhihai Qin, , Yulong He

This study shows that loss of endothelial FSTL1 causes atrial and vein wall fibrosis through SMAD3 activation, leading to heart failure.

Arteriosclerosis Thrombosis and Vascular Biology · Feb 13, 2020Peer-reviewedDevelopmental Biology

Transcriptome Profiling of Mouse Brain and Lung under Dip2A Regulation Using RNA-Sequencing

Rajiv Kumar Sah, Analn Yang, Fatoumata Binta Bah, Salah Adlat, Ameer Ali Bohio, Zin Mar Oo, Chenhao Wang, May Zun Zaw Myint, Noor Bahadar, Luqing Zhang, Xuechao Feng, Yaowu Zheng

The paper identifies differentially expressed genes in brain and lung of Dip2a knockout mice using RNA-Seq and validates their roles in development.

PLoS ONE · Jul 10, 2019Peer-reviewedGenetics