Lymphatics unload VEGFR3 in response to the alteration of VEGFR2-mediated transcriptional programs
T J Li, Xudong Cao, Fei Zhou…·Yulong He
This study shows that VEGFR2 is essential for maintaining lymphatic endothelial identity and its loss alters transcriptional programs, reducing VEGFR3-mediated lymphangiogenesis.