Author

Ruth Shelton

University of LiverpoolORCID 0000-0001-7255-8482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amalia AnthousiiD· 1 shared Fabrizio LombardoiD· 1 shared Giulia BevivinoiD· 1 shared Josephine ShepherdiD· 1 shared Molly Margiotta· 1 shared Poppy PescodiD· 1 shared Tony NolaniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Amalia AnthousiORCID

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1 paper

Recent·Most cited

Measuring the impact of genetic heterogeneity and chromosomal inversions on the efficacy of CRISPR-Cas9 gene drives in different strains of Anopheles gambiae

Poppy Pescod, Giulia Bevivino, Amalia Anthousi, Ruth Shelton, Molly Margiotta, Josephine Shepherd, Fabrizio Lombardo, Tony Nolan

This study evaluates how genetic variation and chromosomal inversions affect CRISPR-Cas9 gene drive homing in Anopheles gambiae strains, finding no significant reduction in homing despite target site heterogeneity.

The CRISPR Journal · Sep 13, 2023Peer-reviewedGenetics