Joana Magalhães

This study shows that Rac1 inhibition prevents cytoskeletal dysfunction in ATTRv-PN by rescuing axonal defects in mice and supporting its therapeutic potential in patients.

This study shows a small-molecule agonist of KIF2C enhances DNA repair and mitigates aging phenotypes in progeria and Down syndrome models.

This study shows that Transthyretin (TTR) promotes axon growth by regulating microtubule dynamics and tubulin acetylation, with restoration of acetylated tubulin rescuing defects in TTR knockout mice.