Bryony RJ Clifton

This study benchmarks AI-generated structural ensembles of membrane proteins against physics-based modeling, showing BioEmu can generate plausible conformations for large membrane proteins with lower computational cost.

This study uses AI and simulations to analyze human rhomboid proteases, revealing that orphan members have narrower gates requiring more energy to open, explaining their substrate limitations.

The paper investigates how the bacterial SMC complex MukBEF loads DNA and how a viral protein inhibits this process through DNA mimicry.