Edward A. Miao

The paper shows that cell junction disruption in keratinocytes leads to translocation of GSDMA and GSDMB from cytoskeleton to plasma membrane without cleavage, but without cytokine release.

The paper shows that cytokines from caspase-1 and RIPK3 pathways antagonize each other during infection, determining immune response outcomes rather than cell death pathways alone.

The paper identifies a population of male germ cells in mice that exhibit non-apoptotic cell death characteristics during G0 arrest, suggesting selection based on cellular health for spermatogonial stem cell precursors.

This study shows Salmonella SPI2 evades NAIP/NLRC4 detection by limiting SsaG expression, despite SsaG being detectable when artificially delivered.

The paper uses spatial transcriptomics to study chemokine expression in granulomas formed by Chromobacterium violaceum infection, showing that CCR2 is critical for macrophage organization and bacterial containment.

The paper identifies NLRP3, NLRP6, and NLRP12 as inflammasomes with distinct expression patterns and activation mechanisms in different cell types.