Blanche Capel

The paper identifies a population of male germ cells in mice that exhibit non-apoptotic cell death characteristics during G0 arrest, suggesting selection based on cellular health for spermatogonial stem cell precursors.

This study shows that glycogen metabolism in Sertoli cells supports germ cell colonization during early testis development through lactate production, highlighting a critical metabolic dependency.

The paper identifies 3D regulatory hubs involved in sex determination using spatial auto-correlation analysis in mouse embryos.

The paper compares single-cell transcriptomic data from turtles, mice, and chickens to show divergence in gonadal cell types and genetic programs across sex determination systems.

The paper characterizes the fetal development and function of the rete ovarii, identifying it as a secretory structure with potential roles in ovarian function and homeostasis.

This study identifies TCF4 as a key regulator of ovarian development by recruiting the Mediator Complex to activate gonadal genes and suppress male-specific pathways.

OoCount provides an automated method for counting and classifying oocytes in 3D fluorescent microscopy images of mouse ovaries using machine learning.

This study analyzes bulk, single-cell, and single nucleus transcriptomes of fetal and adult mouse rete ovarii to identify gene expression signatures and differences across RO regions.

The paper investigates the role of PDGFRA and ERK signaling in fetal testis morphogenesis and Leydig cell development using genetic and molecular approaches.

This study investigates the structural relationships between the ovary and surrounding tissues during mouse development, identifying key interactions that drive ovary morphogenesis.

The paper identifies and characterizes a previously uncharacterized supporting-like cell lineage in developing mouse gonads, showing its origin, specification, and sex-specific differentiation.

The paper shows that deleting Mafb and Maf genes in fetal mouse gonads causes monocyte overproduction and defects in vascularization and testis development.

The paper identifies RUNX1 as a conserved regulator of fetal ovarian supporting cell identity, showing its interaction with FOXL2 in maintaining granulosa cell fate across species.

This study shows that CBX2 represses female fate by maintaining bivalent female-determining genes in male gonads, enabling Sry expression and testis development.