Author

Dong Zhang

Zhejiang UniversityORCID 0000-0001-7297-5083Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Dong Zhang2 papers · Tsinghua University

Biology Disciplines

Click to filter author papers

Biophysics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein structure prediction· 3 Approach:deep learning· 2 Approach:statistical model· 2 Assay:structural biology· 2 Organism:virus· 2 Approach:benchmark study· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Ruhong ZhouiD· 3 shared Yangwei JiangiD· 2 shared Agnieszka RybarczykiD· 1 shared Almudena Ponce-SalvatierraiD· 1 shared Chandran NithiniD· 1 shared Damiano BurattoiD· 1 shared Deyin WangiD· 1 shared Éric WesthofiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

Ruhong ZhouORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

Yanqing Yang, Lulu Qiao, Yangwei Jiang, Zhiye Wang, Dong Zhang, Damiano Buratto, Liquan Huang, Ruhong Zhou

The paper designs and validates high-affinity RNA aptamers for SARS-CoV-2 that match the binding affinity of neutralizing antibodies.

eLife · Jul 14, 2026Peer-reviewedBiophysics

Cross-talk between RNA secondary and three-dimensional structure prediction: a comprehensive study

Deyin Wang, Yangwei Jiang, Linli He, Zhang Linxi, Ruhong Zhou, Dong Zhang

This study benchmarks RNA 3D structure prediction models using varying accuracy 2D structures, finding that 3D models modify input base-pairing interactions and are more sensitive to false positives in 2D structures.

bioRxiv · Jun 23, 2025 · PreprintBiophysics

IsRNAcirc: 3D structure prediction of circular RNAs based on coarse-grained molecular dynamics simulation

Haolin Jiang, Yulian Xu, Yunguang Tong, Dong Zhang, Ruhong Zhou

IsRNAcirc predicts circular RNA 3D structures using coarse-grained molecular dynamics, outperforming template-based methods on a validation set.

PLoS Computational Biology · Oct 28, 2024Peer-reviewedBiophysics

Structure prediction of the druggable fragments in SARS-CoV-2 untranslated regions

Julita Gumna, Maciej Antczak, Ryszard W. Adamiak, Janusz Marek Bujnicki, Shi‐Jie Chen, Feng Ding, Pritha Ghosh, Jun Li, Sunandan Mukherjee, Chandran Nithin, Katarzyna Pachulska‐Wieczorek, Almudena Ponce-Salvatierra, Mariusz Popenda, Joanna Sarzyńska, Tomasz K. Wirecki, , Agnieszka Rybarczyk

The paper reports RNA 3D structure prediction results for SARS-CoV-2 5'- and 3'-UTRs using computational methods and expert analysis.

bioRxiv · Dec 17, 2021 · PreprintBioinformatics