Author

Tomasz K. Wirecki

International Institute of Molecular and Cell BiologyORCID 0000-0001-6539-3640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Research Focus:protein structure prediction· 1 Research Focus:software / tool· 1 Organism:virus· 1

Frequent Co-Authors

Janusz Marek BujnickiiD· 3 shared Almudena Ponce-SalvatierraiD· 2 shared Chandran NithiniD· 2 shared Pritha GhoshiD· 2 shared Agnieszka RybarczykiD· 1 shared Danny IncarnatoiD· 1 shared Dong ZhangiD· 1 shared Eric J. SnijderiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioinformatics

Janusz Marek BujnickiORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 4, 2023

DesiRNA: structure-based design of RNA sequences with a Monte Carlo approach

Tomasz K. Wirecki, Grzegorz Łach, Farhang Jaryani…·Janusz Marek Bujnicki

DesiRNA designs RNA sequences with a Monte Carlo approach, considering structural and sequence constraints, and performs well on the EteRNA benchmark.

1 citation

statistical modelsoftware / tool

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BioinformaticsbioRxivPreprintDec 17, 2021

Structure prediction of the druggable fragments in SARS-CoV-2 untranslated regions

Julita Gumna, Maciej Antczak, Ryszard W. Adamiak…·Agnieszka Rybarczyk

The paper reports RNA 3D structure prediction results for SARS-CoV-2 5'- and 3'-UTRs using computational methods and expert analysis.

2 citations

virusstatistical model

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GeneticsNucleic Acids ResearchPeer-reviewedOct 22, 2020

Genome-wide mapping of therapeutically-relevant SARS-CoV-2 RNA structures

Ilaria Manfredonia, Chandran Nithin, Almudena Ponce-Salvatierra…·Danny Incarnato

This study maps SARS-CoV-2 RNA structures at single-base resolution using SHAPE-MaP, identifies druggable pockets and conserved elements, and highlights targets for antisense therapeutics.

283 citationstop 1%

long-read sequencingexperimental assay

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