Author

Alexandria Nikish

University of PennsylvaniaORCID 0000-0001-7320-4897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abraham J. WaldmaniD· 2 shared Han-Seul RyuiD· 2 shared Jennifer E. Phillips‐CreminsiD· 2 shared Srikar S MuppidiiD· 2 shared Constin LiuiD· 1 shared Dominik PaquetiD· 1 shared Harshini ChandrashekariD· 1 shared Heesun ChoiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Abraham J. WaldmanORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 30, 2025

Persistent chromatin loops shape gene expression plasticity upon stimulation and restimulation of human neurons

Abraham J. Waldman, Kenneth Pham, Katelyn R. Titus…·Jennifer E. Phillips‐Cremins

The paper shows that persistent chromatin loops in human neurons influence gene expression plasticity during and after stimulation, with some loops maintaining repression or activation for up to five days.

DOI 10.1101/2025.09.30.679661

humanscRNA-seq

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Molecular BiologybioRxivPreprintFeb 27, 2024

A multi-looping chromatin signature predicts dysregulated gene expression in neurons with familial Alzheimer's disease mutations

Harshini Chandrashekar, Zoltán Simándi, Heesun Choi…·Jennifer E. Phillips‐Cremins

The paper identifies multi-loop chromatin miswiring in FAD-mutant neurons that correlates with gene expression changes and DLX transcription factor activity.

9 citations

humanscRNA-seq

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