Francesca Rossi

Pan-cancer single-cell and spatial profiling resolves two antigen-presenting CAF lineages: tumor-adjacent mesothelial-like apCAFs and tertiary lymphoid structure-associated fibrocyte-like apCAFs, both secreting pro-tumorigenic SPP1.

This paper identifies geometric and spatial patterns in pancreatic cancer that correlate with aggressive behavior and develops an AI tool to improve clinical evaluation and treatment planning.

This paper identifies cancer cells in scRNA-seq data by combining copy number variation inference with putative driver mutation load to improve downstream analysis.