Kari A. Johnson

This study investigates the role of mGlu2 deletion in Emx1-lineage neurons on behavioral flexibility in mice, finding no significant impact on drug consumption predisposition.

The paper shows that optogenetic stimulation of thalamic terminals in the dorsomedial striatum reinforces operant behavior, and that mGlu2 activation limits this reinforcement.

This study shows that mGlu5 PAMs increase Akt and GSK3β phosphorylation in rat brain regions, suggesting a potential mechanism for their antipsychotic-like effects.