Author

Chiara Balestrieri

IRCCS Ospedale San RaffaeleORCID 0000-0001-7362-3530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:batch correction / integration· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1

Frequent Co-Authors

Giovanni TononiD· 2 shared Alessandro CarugoiD· 1 shared Andrea VialeiD· 1 shared Angela K. DeemiD· 1 shared Ben VanderkrukiD· 1 shared Brad G. HoffmaniD· 1 shared Cecilia S. LeungiD· 1 shared Charles A. DykeiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Giovanni TononORCID

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2 papers

Recent·Most cited

WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer

Francesca Citron, I-Lin Ho, Chiara Balestrieri, Zhaoliang Liu, Er-Yen Yen, Luca Cecchetto, Luigi Perelli, Li Zhang, Luis A Castillo, Nicholas Blazanin, Charles A. Dyke, Rutvi Shah, Sergio Attanasio, Sanjana Srinivasan, Ko‐Chien Chen, , Giulio Francesco Draetta

This study shows that disrupting the WRAD core in pancreatic cancer leads to DNA replication errors, immune response activation, and improved response to immune checkpoint inhibitors.

bioRxiv · Oct 21, 2024 · PreprintCancer Biology

Scalable Integration of Multiomic Single Cell Data Using Generative Adversarial Networks

Valentina Giansanti, Francesca Giannese, Oronza Antonietta Botrugno, Giorgia Gandolfi, Chiara Balestrieri, Marco Antoniotti, Giovanni Tonon, Davide Cittaro

This paper introduces a framework for integrating multiomic single-cell data using Wasserstein GANs, enabling analysis of more than two modalities with reduced computational burden.

Bioinformatics · Apr 30, 2024Peer-reviewedBioinformatics