GPR43 in Eosinophils Prevents the Emergence of Pathogenic Siglec-Fhi Neutrophils in Allergic Airway Inflammation
Jihyun Yu, Seongryong Kim, Hyun-Sup Song, Jieun Kim, Woojung Shin, Jong-Eun Park, Ikuo Kimura, Hye Young Kim, You‐Me Kim
The paper shows that eosinophils modulate neutrophil differentiation into pathogenic Siglec-Fhi neutrophils via GPR43, exacerbating allergic airway inflammation.
Nature Communications · Nov 26, 2025Peer-reviewedImmunology